Amanda Seyfried

Daphne Blake (voice)

Acting

Christina Hendricks

Officer Jaffe (voice)

Acting

Frank Welker

Scooby-Doo / Pterodactyl (voice)

Acting

Mckenna Grace

Young Daphne (voice)

Acting

Gina Rodriguez

Velma Dinkley (voice)

Acting

Justina Milagros Machado

Jamie Rivera (voice)

Acting

Zac Efron

Fred Jones (voice)

Acting

Ariana Greenblatt

Young Velma (voice)

Acting

Will Forte

Shaggy Rogers (voice)

Acting

Mark Wahlberg

Blue Falcon (voice)

Acting

Iain Armitage

Young Shaggy (voice)

Acting

Pierce Gagnon

Young Fred (voice)

Acting

Henry Winkler

Keith (voice)

Acting

Jason Isaacs

Dick Dastardly (voice)

Acting

Kiersey Clemons

Dee Dee Skyes (voice)

Acting

Ken Jeong

Dynomutt, Dog Wonder (voice)

Acting

Tracy Morgan

Captain Caveman (voice)

Acting

Simon Cowell

Simon Cowell (voice)

Acting

Harry Perry

Harry Perry (voice)

Acting

Kevin Heffernan

Bike Cop Gary (voice)

Acting

John DiMaggio

Restaurant Owner (voice)

Acting

Ira Glass

Ira Glass (voice)

Acting

Henry Kaufman

Chad / Chet (voice)

Acting

Maya Erskine

Judy Takamoto (voice)

Acting

Billy West

Muttley (voice)

Acting

Don Messick

Muttley (archive audio) (voice)

Acting

Fred Tatasciore

Cerberus (voice)

Acting

Kennedy Peil

Indira Knight (voice)

Acting

John McDaniel

Hal Murphy (voice)

Acting

Ryan Folsey

Beach Guy (voice)

Editing

Pam Coats

Mrs. Rogers (voice)

Production

Tony Cervone

Ghost / Mr. Rigby / Alice (voice)

Directing

Alex Kauffman

Officer North (voice)

Acting

Vanara Taing

Baby Rotten (voice)

Editing

Sarah Lancia

Dispatcher Stevens (voice)

Acting

Eric Cowell

Ben (voice)

Acting

Maven Morgan

Kari (voice)

Acting

Adam Sztykiel

Officer Casey (voice)

Writing

Michael Kurinsky

Samuel Colton (voice)

Art